Baccharis trimera herb
Baccharis trimera (Less) DC (Asteraceae), known in Brazil as carqueja, has been popularly used to treat liver diseases, rheumatism, diabetes, as well as digestive, hepatic and renal disorders. This herb is also used for energy enhancement and as an aphrodisiac.
Animal studies show
Baccharis trimera has anti-inflammatory properties which seem to be due, at
least partly, to the inhibition of prostaglandin biosynthesis. This plant also
has compounds that relax corpus cavernosum smooth muscle. Bacchars trimera may
also help decrease food intake.
Argentinian plant extracts with relaxant effect on the smooth muscle of the
corpus cavernosum of guinea pig.
Phytomedicine. 2003 November. Hnatyszyn O, Moscatelli V, Garcia J, Rondina R,
Costa M, Arranz C, Balaszczuk A, Ferraro G, Coussio JD.
Cátedra de Farmacognosia, IQUIMEFA (UBA-CONICET), Facultad de Farmacia y
Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina.
Extracts of different polarity from Baccharis trimera, Haplopappus rigidus
Huperzia saururus, Maytenus ilicifolia, Satureja parvifolia and Senecio
eriophyton were tested for their relaxant activity on smooth muscle using L-phenylephrine
precontracted strips of corpus cavernosum obtained from Guinea pigs. Highly
significant and dose dependent results were obtained with the dichloromethane
extracts of Huperzia saururus (87% of relaxation at the dose of 10 mg/ml),
Satureja parvifolia (95% of relaxation at 2.5 mg/ml) and Senecio eriophyton (94%
of relaxation at 5 mg/ml). Similar effects were observed with the methanol
extracts of Huperzia saururus (88% of relaxation at 10 mg/ml) and Satureja
parvifolia (84% of relaxation at 10 mg/ml). These results were comparable to
those obtained with the dichloromethane and methanol extracts of the well known
Mexican species
Turnera
diffusa. Moreover, the aqueous extract of Haplopappus rigidus and the aqueous
and methanol extracts of Senecio eriophyton were highly effective in a dose
dependent manner (more than 90% of relaxation at the dose of 10 mg/ml).
Significant results, but with a lower overall relaxant activity (about 70% of
relaxation at 10 mg/ml), could also be obtained with the aqueous extract of
Satureja parvifolia and with the dichlormethane and methanol extracts of
Baccharis trimera and Maytenus ilicifolia. The positive controls with Sildenafil
citrate at doses ranging from 0.35 to 35 microg/ml yielded moderate effects (up
to 46% of relaxation at 35 microg/ml). The effects observed in the present study
seem to validate the folk medicinal use of the tested plants and open new ways
in the search for natural products with vasodilatory effects.
Effect of the extracts and fractions of Baccharis trimera and Syzygium cumini
on glycaemia of diabetic and non-diabetic mice.
J Ethnopharmacol. 2005 December. Oliveira AC, Endringer DC, Amorim LA, das
Graças L Brandão M, Coelho MM. Faculty of Pharmacy, Federal University of Minas
Gerais, Belo Horizonte MG, Brazil.
W investigated the effects of extracts and fractions of Baccharis trimera and
Syzygium cumini on glycaemia of diabetic and non-diabetic mice. Crude ethanolic
extracts and aqueous and butanolic fractions of the aerial parts of Baccharis
trimera and leaves of Syzygium cumini were evaluated. None of the extracts or
fractions (200 or 2000 mg/kg, per os) induced any effect after acute
administration. Seven-day treatment with crude ethanolic and aqueous and
butanolic fractions (200-2000 mg/kg, twice daily, per os) of Syzygium cumini
reduced glycaemia of non-diabetic mice. However, this effect was associated with
a reduction of food intake and body weight, indicating that this may not be a
genuine hypoglycaemic effect. In diabetic mice, only the aqueous fraction of
Baccharis trimera (2000 mg/kg, twice daily, per os) reduced the glycaemia after
a 7-day treatment. This effect was not associated with a body weight reduction.
The results suggest that Baccharis trimera presents a potential antidiabetic
activity and indicate that food intake and body weight must be determined when
evaluating metabolic parameters after prolonged administration of plant
extracts.
Substnaces in Baccharis
The active constituents are saponins in which echinocystic acid (or its
enantiomer) is the major aglycone, quinic acids, and also flavonoids such as
rutin, and ent-clerodane-type diterpenoids. Dilactonic clerodane diterpene in Baccharis
trimera helps relax smooth muscles.
Baccharis species include
Baccharis articulata (Lam.) Persoon. is promoted in Brazil as having weight loss
properties.
Baccharis crispa
Baccharis genistelloides Persoon var. trimera (Less.) DC,
Baccharis milleflora (Less.) DC
Baccharis usterii
Aphrodisiac herbs
available over the counter
These include maca, tongkat ali, butea superba, cnidium monnieris,
Tribulus-Terrestris extract, mucuna pruriens, horny
goat weed, avena sativa, LJ100, muira puama, catuaba, ginger, cistanches, and
yohimbe bark extract.
Aphrodisiacs natural home