Casimiroa edulis White Sapote Zapote blanco
Zzapote blanco (Casimiroa edulis), is consumed in many parts of the world, including Central America and Asia. The tropical fruit has zapotin (5,6,2',6'-tetramethoxyflavone). The seed extract may have aphrodisiac properties.
The hydroalcoholic extract of Casimiroa edulis may contain sedative principles with potential anxiolytic and antidepressant properties, which need further investigation.
Aqueous extracts of lyophilized seeds of Casimiroa edulis have ndothelium-dependent vasorelaxing activity on rat mesenteric arterial beds.
Probable neuro sexual mode of action of casimiroa edulis seed extract verses
sildenafil citrate (viagratm) on mating behavior in normal male rats.
Pak J Pharm Sci. 2008 Jan;21(1):1-6. Ali ST, Rakkah NI. Department of
Physiology, Faculty of Medicine, Umm-Al-Qura University, P.O. Box 7607, Makkah,
Saudi Arabia.
The present study deals with the aphrodisiac actions of the aqueous extract of
the seeds of the hypotensive plant Casimiroa edulis on the sexual behavior of
normal male rats. In this investigation 30 healthy male Wister strain white
albino rats showing the brisk sexual activity age 15 weeks, weighing 400-450
grams were included. Female rats were artificially brought into estrous by
hormonal treatment. Receptivity was checked by exposing them to the male rats
and the most receptive females were selected for the stud The mating responses
including Mounting Frequency (MF), Intromission Frequency (IF), Mounting Latency
(ML), Intromission Latency (IL), Ejaculatory Latency in first and second series
(EL1 and EL2) and Post Ejaculatory Interval (PEI) were recorded after treating
the animals with 250 mg/kg casimiroa edulis extract (test reference) and 5 mg/kg
sildenafil citrate (standard reference) respectively orally per day for 7 days.
Both the groups exhibited a significant increase in Mounting Frequency,
Intromission Frequency, and first and second ejaculatory latencies, where as
Mounting and Intromission latencies and the Post Ejaculatory Interval showed a
significant reduction than the controls. Although a similar pattern of mating
behavior was observed among the test and the standard groups, however in all the
cases as expected, sildenafil produced greater activity than the casimiroa
edulis extract. These results suggest the possibility of a similar mode of
action of casimiroa edulis and sildenafil citrate on mating behavior in these
animals. Our work reported in this research thus provide preliminary evidence
that the aqueous seed extract of casimiroa edulis possesses alphrodisiac
activity and may be used as an alternative drug therapy to restore sexual
functions probably via a neurogenic mode of action.
Aphrodisiac herbs available over
the counter
These include maca, tongkat ali, butea superba, cnidium monnieris, tribulus
terrestris extract, mucuna pruriens,
Horny-Goat-Weed, avena sativa, LJ100, muira puama,
catuaba, ginger, cistanches, and yohimbe bark extract.
Aphrodisiacs natural home