Casimiroa edulis White Sapote Zapote blanco

Zzapote blanco (Casimiroa edulis), is consumed in many parts of the world, including Central America and Asia. The tropical fruit has zapotin (5,6,2',6'-tetramethoxyflavone). The seed extract may have aphrodisiac properties.

The hydroalcoholic extract of Casimiroa edulis may contain sedative principles with potential anxiolytic and antidepressant properties, which need further investigation.

Aqueous extracts of lyophilized seeds of Casimiroa edulis have ndothelium-dependent vasorelaxing activity on rat mesenteric arterial beds.

Probable neuro sexual mode of action of casimiroa edulis seed extract verses sildenafil citrate (viagratm) on mating behavior in normal male rats.
Pak J Pharm Sci. 2008 Jan;21(1):1-6. Ali ST, Rakkah NI. Department of Physiology, Faculty of Medicine, Umm-Al-Qura University, P.O. Box 7607, Makkah, Saudi Arabia.
The present study deals with the aphrodisiac actions of the aqueous extract of the seeds of the hypotensive plant Casimiroa edulis on the sexual behavior of normal male rats. In this investigation 30 healthy male Wister strain white albino rats showing the brisk sexual activity age 15 weeks, weighing 400-450 grams were included. Female rats were artificially brought into estrous by hormonal treatment. Receptivity was checked by exposing them to the male rats and the most receptive females were selected for the stud The mating responses including Mounting Frequency (MF), Intromission Frequency (IF), Mounting Latency (ML), Intromission Latency (IL), Ejaculatory Latency in first and second series (EL1 and EL2) and Post Ejaculatory Interval (PEI) were recorded after treating the animals with 250 mg/kg casimiroa edulis extract (test reference) and 5 mg/kg sildenafil citrate (standard reference) respectively orally per day for 7 days. Both the groups exhibited a significant increase in Mounting Frequency, Intromission Frequency, and first and second ejaculatory latencies, where as Mounting and Intromission latencies and the Post Ejaculatory Interval showed a significant reduction than the controls. Although a similar pattern of mating behavior was observed among the test and the standard groups, however in all the cases as expected, sildenafil produced greater activity than the casimiroa edulis extract. These results suggest the possibility of a similar mode of action of casimiroa edulis and sildenafil citrate on mating behavior in these animals. Our work reported in this research thus provide preliminary evidence that the aqueous seed extract of casimiroa edulis possesses alphrodisiac activity and may be used as an alternative drug therapy to restore sexual functions probably via a neurogenic mode of action.

Aphrodisiac herbs available over the counter
These include maca, tongkat ali, butea superba, cnidium monnieris, tribulus terrestris extract, mucuna pruriens, Horny-Goat-Weed, avena sativa, LJ100, muira puama, catuaba, ginger, cistanches, and yohimbe bark extract.

Aphrodisiacs natural home