Casimiroa edulis White fruit Sapote Zapote blanco

Zapote blanco, Casimiroa edulis, is consumed in many parts of the world, including Central America and Asia. The tropical fruit has zapotin (5,6,2',6'-tetramethoxyflavone). The seed extract may have aphrodisiac properties.

As of April 2009, we have not seen human research with Casimiroa edulis herb.

Properties of Casimiroa edulis herb
The hydroalcoholic extract of Casimiroa edulis may contain sedative principles with potential anxiolytic and antidepressant properties, which need further investigation. Aqueous extracts of lyophilized seeds of Casimiroa edulis have endothelium-dependent vasorelaxing activity on rat mesenteric arterial beds.

Casimiroa edulis sexual benefits
Probable neuro sexual mode of action of casimiroa edulis seed extract verses sildenafil citrate (viagratm) on mating behavior in normal male rats.
Pak J Pharm Sci. 2008 Jan;21(1):1-6. Ali ST, Rakkah NI. Department of Physiology, Faculty of Medicine, Umm-Al-Qura University, P.O. Box 7607, Makkah, Saudi Arabia.
The present study deals with the aphrodisiac actions of the aqueous extract of the seeds of the hypotensive plant Casimiroa edulis on the sexual behavior of normal male rats. In this investigation 30 healthy male Wister strain white albino rats showing the brisk sexual activity age 15 weeks, weighing 400-450 grams were included. Female rats were artificially brought into estrous by hormonal treatment. Receptivity was checked by exposing them to the male rats and the most receptive females were selected for the stud The mating responses including Mounting Frequency (MF), Intromission Frequency (IF), Mounting Latency (ML), Intromission Latency (IL), Ejaculatory Latency in first and second series (EL1 and EL2) and Post Ejaculatory Interval (PEI) were recorded after treating the animals with 250 mg/kg casimiroa edulis extract (test reference) and 5 mg/kg sildenafil citrate (standard reference) respectively orally per day for 7 days. Both the groups exhibited a significant increase in Mounting Frequency, Intromission Frequency, and first and second ejaculatory latencies, where as Mounting and Intromission latencies and the Post Ejaculatory Interval showed a significant reduction than the controls. Although a similar pattern of mating behavior was observed among the test and the standard groups, however in all the cases as expected, sildenafil produced greater activity than the casimiroa edulis extract. These results suggest the possibility of a similar mode of action of casimiroa edulis and sildenafil citrate on mating behavior in these animals. Our work reported in this research thus provide preliminary evidence that the aqueous seed extract of casimiroa edulis possesses aphrodisiac activity and may be used as an alternative drug therapy to restore sexual functions probably via a neurogenic mode of action.

Aphrodisiac herbs available over the counter
These include maca root, tongkat ali root, epimedium extract, butea superba, ginseng, tribulus terrestris extract, mucuna pruriens, avena sativa, LJ100, muira puama, catuaba, ginger, cistanches, and yohimbe bark extract.

Chemical composition of the leaf essential oil of Casimiroa edulis La Llave & Lex. (Rutaceae) from Monteverde, Costa Rica.
Nat Prod Commun. 2009 Mar; Miller SL, Haber WA, Setzer WN. Department of Chemistry, University of Alabama in Huntsville, Huntsville, Alabama 35899, USA.
The leaf essential oil of Casimiroa edulis (Rutaceae), collected from Monteverde, Costa Rica, has been obtained by hydrodistillation and analyzed by GC-MS. The leaf oil was dominated by sesquiterpene hydrocarbons, predominately germacrene D (16-22%) and (E)-caryophyllene (16-17%), consistent with the traditional use of this plant as a sedative, sleep inducer and hypotensive.